http://www.winpatrol.com/download.html

WinPatrol takes snapshot of your critical system resources and alerts you to any changes that may occur without your knowledge. WinPatrol was the pioneer in using a heuristic behavioral approach to detecting attacks and violations of your computing environment. It continues to be one of the most powerful system monitors while staying a single small programs.

As a robust SECURITY MONITOR , WinPatrol will alert you to hijackings, malware attacks and critical changes made to your computer without your permission. As a MULTI PURPOSE SUPPORT UTILITY WinPatrol replaces multiple system utilities with its enhanced functionality. Traditional security programs scan your hard drive searching for previously identified threats. WinPatrol will alert you to dangerous new programs while others prepare to update their definition/signature virus data files.
Supports Windows 98 - Windows 7 including x64 systems