Both teams are capable of the next:

HUMANS:
They look for safe places and they stay there until the game ends.
They are capable of throwing fire grenades, frost and flares.
Depending on the darkness of the map, a bot will not be able to see long distances.
They are sensitive to the light and glow of zombies.
The bots will flee and perform evasive maneuvers, with jumps to avoid being infected.
These bots can predict the walls behind them and make decisions to try not to get caught.
New system to aim targets, more adjusted to how a real player would aim. It will depend on the bot's ability (Skill).
They can decide whether or not to break a platform through which they have passed,
thus preventing the zombies (Sometimes other humans, as usually happens online) to climb or reach the place.

ZOMBIES
Able to throw infection bombs (If they have enough ammo packs).
They do not use the radio.
When they are strongly wounded, they try evasion and jumping maneuvers to avoid Headshots.
They can break sandbags, introduced in the game by the plugin "zp-sandbags".
If there is a human in a high place, the zombies will make a "ladder"; that is,
they will crouch down and jump on top of others to help reach the human.
New special IA for Nemesis and Assassins, they can use Longjump and they will try to reach humans in higher places
They play as a team and warn others where the humans are; attacking in hordes.
They can predict the movements of humans when they are pursuing them, shortening distances and cutting off escape routes.(Only if you use Zombie plague: Apocalypse

Official video-trailer: https://www.youtube.com/watch?v=VQHvEx9iyOo